Diagnostic utility of Liquid-Based Cytology in the Diagnosis of Lung Cancer

Lung cancer is worldwide most common cause of cancer related death. A use of LiquidBased Cytology (LBC) in non-gynae has been increasing. Aims: To assess the diagnostic utility of LBC in the diagnosis of lung cancer from the aspirated material either by endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) or CT guided trans thoracic needle aspiration (TTFNA) from lung mass. Methods and Material: This study was conducted at the Department of Pathology, tertiary hospital. Sixty one malignant cases were included in our study and their respective cytology smear has been prepared by both techniques LBC and Conventional Smear (CS), considered histopathology as a gold standard for concordance of the diagnosis. Results: Number of malignant case were diagnosed by LBC 72.3% where by conventional method 60.66% which does indicated a there is no statistical significance between the two groups (P = 0.180) but still few cases diagnosed by LBC were higher than CS, due to improvement of adequacy in LBC (86.89%) as compared to CS (65.57%). Conclusions: We can conclude that LBC was superior to CS in the diagnosis of aspirated material from the lung mass because it improves the adequacy of samples, as it is depend on automation technique.